The approach taken with other primary liver tumors is generally the same as for hepatocellular carcinoma . Patients with these other tumors are more likely to be candidates for surgery because they usually do not have underlying liver disease.

Angiosarcoma & Hemangioendothelioma 
These diseases are less predictable than hepatocellular carcinoma and survival is variable.
• If they have not spread at the time of diagnosis, surgery should be considered.
• As in hepatocellular carcinoma, no systematic study of adjuvant chemotherapy or radiotherapy has been
  done.
• Localized unresectable disease may respond to the same intravenous chemotherapy used for sarcomas and
  the tumors may occasionally shrink enough to allow the surgeon to remove them completely.
• Advanced disease is approached in the same way as a sarcoma.

Adenocarcinoma 
This type of tumor is approached in the same way as hepatocellular carcinoma. Its prognosis is similar.